Identification of Transcriptional Modules and Key Genes in Chickens Infected with Salmonella enterica Serovar Pullorum Using Integrated Coexpression Analyses

Table 1

Module preservation and functions.

Module	Size	summary	Function
Lightyellow	126	5.42	Nucleus
Lightgreen	145	0.67	Jak-STAT signaling pathway
Grey60	145	7.49	Extracellular matrix
			Cytoskeleton
Lightcyan	155	0.52	Anchored to membrane
Midnightblue	159	5.78	Cytoplasm ;
			Organelle membrane
			Endomembrane system
Cyan	181	8.71	Cell adhesion molecules
			Cell adhesion
Salmon	248	2.14	Neuroactive ligand-receptor interaction
Tan	287	4.86	Lysosome
Greenyellow	293	6.58	Ligase activity
Purple	298	10.93	Proteasome complex
			Regulation of cytokine biosynthetic process
			Toll-like receptor signaling pathway
Magenta	357	1.82	G-Protein coupled receptor activity
Pink	418	13.36	Cellular macromolecular complex assembly
Black	599	1.97	Postsynaptic membrane
			Synapse
Red	648	14.89	Signal transducer activity
			Multicellular organism development
Green	1056	27.63	Cell cycle phase
			DNA replication
			Response to DNA damage stimulus
			DNA repair
			Cytoskeleton organization
Yellow	1122	32.83	Glucose catabolic process
			Glycolysis/gluconeogenesis
			Glycolysis
			Glucose metabolic process
Brown	1349	18.99	ABC transporters
Blue	2581	43.01	Immune system process
			Induction of apoptosis
			Antigen processing and presentation
			Lysosome
			Defense response to bacterium
Turquoise	2998	51.56	Nervous system development
			Focal adhesion
			Wnt signaling pathway
			Regulation of actin cytoskeleton
			TGF-beta signaling pathway

Note. The column “Size” gives the gene numbers contained in every module. “ summary” gives the score of module preservation. “Function” gives the module functions enriched by DAVID.