Review Article

The Roles of Thrombospondins in Hemorrhagic Stroke

Table 1

Diverse roles of TSP-1.

Binding receptors or moleculesFunctionsReferences

CD36Antiangiogenic[13, 4550]
Proinflammatory[15, 51]
Anti-inflammatory[17, 45]
Proapoptotic[14]
Profibrogenic[21, 52]

CD47Antiangiogenic[49]
Anti-inflammatory[45]
Proapoptotic[18, 19]

TNF-R1Proapoptotic[20]

TGF-βAnti-inflammatory[53]
Profibrogenic[54]

MMP-9Antiangiogenic[55, 56]

α2δ-1, neuroligin 1Prosynaptogenic[22, 24]