Research Article

Dexamethasone Modulates Nonvisual Opsins, Glucocorticoid Receptor, and Clock Genes in Danio rerio ZEM-2S Cells

Figure 6

Time course of opn4m1 (a) and opn4m2 (b) gene expression in D. rerio ZEM-2S cells exposed to LD (12 : 12) cycles and subject to 6 medium changes (control) or 3 DEX pulses. Each value is the mean ( flasks), ±SEM, of transcripts normalized by ribosomal 18S RNA and expressed relative to 24 h average of each gene after 2 medium changes. A significantly different from B and C from D demonstrated by one way ANOVA, followed by Tukey (). Asterisk means significantly different from the respective control at the same time point (, two way ANOVA followed by Bonferroni).
(a) opn4m1
(b) opn4m2