Microarray Analysis and Detection of MicroRNAs Associated with Chronic Thromboembolic Pulmonary Hypertension

Table 5

Functional enrichment analysis of the target genes of the key miRNAs.

Term	Description	Count	value
Upregulated
GO:0060736	Prostate gland growth	3
GO:0006366	Transcription from RNA polymerase II promoter	10
GO:0045893	Positive regulation of transcription, DNA-templated	10
GO:0060749	Mammary gland alveolus development	3
GO:0018105	Peptidyl-serine phosphorylation	5
hsa05205	Proteoglycans in cancer	7
hsa04310	Wnt signaling pathway	6
hsa04012	ErbB signaling pathway	5
hsa05200	Pathways in cancer	9
hsa04916	Melanogenesis	5
Downregulated
GO:0010557	Positive regulation of macromolecule biosynthetic process	10
GO:0006820	Anion transport	5
GO:0048666	Neuron development	7
GO:0031328	Positive regulation of cellular biosynthetic process	10
GO:0030278	Regulation of ossification	4
hsa04020	Calcium signaling pathway	5

Term represents the identification number of GO-BP or KEGG pathway. Description represents the name of the GO-BP or KEGG pathway. Counts represent the number of genes enriched in the GO-BP or KEGG pathway.