Research Article

In Vitro/In Silico Study on the Role of Doubling Time Heterogeneity among Primary Glioblastoma Cell Lines

Figure 7

In vitro spheroidal growth as opposed to in silico for all four cell types with the final chosen sets of doubling times as shown in Table 1 and fixed proliferation depth equal to 2. Two additional simulated growth curves are depicted with different proliferation depth values for the GBP06 (, yellow dash dotted line) and the GBP08 (, purple dash dotted line) spheroids.