Research Article

In Vitro/In Silico Study on the Role of Doubling Time Heterogeneity among Primary Glioblastoma Cell Lines

Table 1

Mean cell sizes and doubling times (±standard deviation) as estimated from the in vitro experiments for the respective cell lines (first column). The in silico values used to initialize the HDC model regarding the doubling time are also shown.

Cell typeIn vitro estimationsIn silico values
Cell diameter (μm)Doubling time (h)Doubling time (h)

U87MG21.530.8 ± 2.533
GBP031925.4 ± 0.525
GBP061623.5 ± 0.723
GBP081523.0 ± 1.522