Research Article

Heterogeneous Periostin Expression in Different Histological Variants of Papillary Thyroid Carcinoma

Table 2

PN expression in intratumor stroma and clinicopathological characteristics of PTC.

Clinicopathologic features Case number PNOR
(95% CI)
Low score High score
#%#%#% value

Sex
Female1.07
(0.23–4.99)
Male

Age
<451.05
(0.55–6.84)
>45

Tumor stage
Stages I, II0.28
(0.07–0.99)
Stages III, IV

Histologic subtype
Conventional0.40
(0.08–1.90)
Follicular
Macrofollicular1.00
(0.15–6.64)
Tall cells3.00
(0.22–39.60)
Oncocytic1.20
(0.12–11.86)

Multifocality
No0.37
(0.08–1.56)
Yes

Tumor size
<2.18 cm2.52
(0.71–8.96)
>2.18 cm

Lymphovascular invasion
Absent0.48
(0.11–2.04)
Present

Lymph node metastasis
Absent0.11
(0.006–2.07)
Present

Extrathyroidal invasion
Absent0.16
(0.03–0.67)
Present

: chi-square test; OR: odd ratio; CI: confidence interval.