Research Article
Heterogeneous Periostin Expression in Different Histological Variants of Papillary Thyroid Carcinoma
Table 2
PN expression in intratumor stroma and clinicopathological characteristics of PTC.
| Clinicopathologic features | Case number | PN | | OR (95% CI) | Low score | High score | # | % | # | % | # | % | value |
| Sex | | Female | | | | | | | | 1.07 (0.23–4.99) | Male | | | | | | |
| Age | | <45 | | | | | | | | 1.05 (0.55–6.84) | >45 | | | | | | |
| Tumor stage | | Stages I, II | | | | | | | | 0.28 (0.07–0.99) | Stages III, IV | | | | | | |
| Histologic subtype | | Conventional | | | | | | | | 0.40 (0.08–1.90) | Follicular | | | | | | | Macrofollicular | | | | | | | 1.00 (0.15–6.64) | Tall cells | | | | | | | 3.00 (0.22–39.60) | Oncocytic | | | | | | | 1.20 (0.12–11.86) |
| Multifocality | | No | | | | | | | | 0.37 (0.08–1.56) | Yes | | | | | | |
| Tumor size | | <2.18 cm | | | | | | | | 2.52 (0.71–8.96) | >2.18 cm | | | | | | |
| Lymphovascular invasion | | Absent | | | | | | | | 0.48 (0.11–2.04) | Present | | | | | | |
| Lymph node metastasis | | Absent | | | | | | | | 0.11 (0.006–2.07) | Present | | | | | | |
| Extrathyroidal invasion | | Absent | | | | | | | | 0.16 (0.03–0.67) | Present | | | | | | |
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: chi-square test; OR: odd ratio; CI: confidence interval.
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