Insulin Resistance and Its Association with Metabolic Syndrome in Korean Children
Table 3
Odds ratio (OR) and 95 confidence interval (95% CI) of metabolic abnormalities according to HOMA-IR quartiles.
Metabolic abnormalities
HOMA-IR quartiles (values)
Q1
Q2
Q3
Q4
(<1.13)
(1.13–1.65)
(1.65–2.65)
(>2.65)
WC ≥ 90 percentile
Unadjusted OR
Referent
1.48
3.89
8.40
95% CI
-
0.78–2.78
2.22–6.80
4.89–14.42
value
-
0.225
<0.001
<0.001
Adjusted OR
Referent
0.58
1.10
1.68
95% CI
-
0.37–0.89
0.73–1.63
1.12–2.50
value
-
0.189
0.813
0.182
SBP ≥ 90 percentile
Unadjusted OR
Referent
1.36
1.70
2.41
95% CI
-
0.75–2.43
0.96–2.97
1.40–4.12
value
-
0.303
0.065
0.001
Adjusted OR
Referent
1.14
1.34
1.90
95% CI
-
0.83–1.57
0.97–1.85
1.35–2.66
value
-
0.662
0.344
0.051
DBP ≥ 90 percentile
Unadjusted OR
Referent
1.00
1.33
1.99
95% CI
-
0.63–1.57
0.86–2.04
1.31–3.01
value
-
1.000
0.198
0.001
Adjusted OR
Referent
0.91
1.25
2.03
95% CI
-
0.71–1.16
0.97–1.59
1.56–2.63
value
-
0.687
0.349
0.005
Glucose ≥ 100 mg/dL
Unadjusted OR
Referent
4.15
5.63
15.62
95% CI
-
1.76–9.73
2.45–12. 92
7.04–34.63
value
-
0.001
<0.001
<0.001
Adjusted OR
Referent
4.97
6.70
19.54
95% CI
-
3.07–8.03
4.32–11.1
12.1–31.3
value
-
0.001
<0.001
<0.001
TG ≥ 150 mg/dL
Unadjusted OR
Referent
2.50
7.43
15.11
95% CI
-
0.88–7.33
2.85–19.34
5.95–38.35
value
-
0.083
<0.001
<0.001
Adjusted OR
Referent
1.81
4.56
7.64
95% CI
-
1.06–3.06
2.82–7.34
4.73–12.34
value
-
0.246
0.001
<0.001
TC ≥ 200 mg/dL
Unadjusted OR
Referent
0.94
1.13
2.34
95% CI
-
0.58–1.54
0.70–1.80
1.45–3.45
value
-
0.817
0.618
<0.001
Adjusted OR
Referent
0.92
1.06
1.83
95% CI
-
0.70–1.20
0.81–1.37
1.41–2.38
value
-
0.748
0.820
0.016
HDL-C < 40 mg/dL
Unadjusted OR
Referent
1.09
3.33
5.39
95% CI
-
0.71–1.67
2.333–4.77
3.81–7.61
value
-
0.830
<0.001
<0.001
Adjusted OR
Referent
1.00
2.52
2.70
95% CI
-
0.64–1.54
1.74–3.64
1.86–3.91
value
-
0.999
0.010
0.006
WC: waist circumference; SBP: systolic blood pressure; DBP: diastolic blood pressure; TG: triglycerides; HDL-C: high density lipoprotein-cholesterol. Adjusted for age and sex. Adjusted OR for age, sex, BMI, and body fat percentage.
