Inverse Relationship between Serum VEGF Levels and Late In-Stent Restenosis of Drug-Eluting Stents
Table 1
Baseline and laboratory characteristics of the study population.
Characteristic
ISR ()
Non-ISR ()
value
Procedure age, years
64.57 ± 9.26
61.62 ± 10.18
0.06
Male gender, (%)
66 (83.5)
69 (87.3)
0.23
Hypertension, (%)
52 (62.5)
53 (67.1)
0.86
Diabetes mellitus, (%)
32 (40.5)
26 (32.9)
0.32
Current smoker, (%)
19 (24.1)
18 (22.8)
0.85
LVEF (%)
61.74 ± 7.31
63.21 ± 5.87
0.17
Creatinine (μmol/L)
79.36 ± 24.18
80.77 ± 25.27
0.72
TC (mmol/L)
3.30 (3.01, 4.07)
3.37 (2.73, 4.10)
0.43
TG (mmol/L)
1.22 (0.96, 1.74)
1.37 (0.91, 2.03)
0.37
LDL-C (mmol/L)
1.86 ± 0.86
1.62 ± 0.77
0.07
HDL-C (mmol/L)
1.00 ± 0.33
1.01 ± 0.38
0.93
hs-CRP (mg/L)
1.3 (0.3, 4.0)
0.5 (0.17, 1.65)
0.05
VEGF (pg/mL)
96.34 (48.18, 174.14)
179.14 (93.59, 307.74)
<0.01
Values are presented as number (%), mean value ± standard deviation, or median (interquartile range). LVEF = left ventricular ejection fraction; hs-CRP = high-sensitivity C-reactive protein; VEGF = vascular endothelial growth factor; TC = total cholesterol; TG = total triglyceride; LDL-C = low-density lipoprotein cholesterol; HDL-C = high-density lipoprotein cholesterol.
