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BioMed Research International
Volume 2017 (2017), Article ID 8732351, 7 pages
https://doi.org/10.1155/2017/8732351
Clinical Study

Comparison of Nonspherical Polyvinyl Alcohol Particles and Microspheres for Prostatic Arterial Embolization in Patients with Benign Prostatic Hyperplasia

1Department of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea
2Soo Radiology Clinic, Guri-si, Gyeonggi-do, Republic of Korea
3Department of Urology, Dongin Hospital, Gangneung-si, Gangwon-do, Republic of Korea
4Department of Urology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea

Correspondence should be addressed to Sang Woo Park

Received 20 January 2017; Revised 9 April 2017; Accepted 28 May 2017; Published 22 June 2017

Academic Editor: Arnaldo Scardapane

Copyright © 2017 Jin Ho Hwang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose. To report early results following prostatic artery embolization (PAE) and compare outcomes between nonspherical polyvinyl alcohol (PVA) particles and microspheres to treat lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH). Methods. PAE was performed in nine patients (mean age: 78.1 years) with symptomatic BPH. Embolization was performed using nonspherical PVA particles (250–355 μm) in four patients and microspheres (300–500 μm) in five patients. Results. PAE was technically successful in all nine patients (100%). During a mean follow-up of 10.1 months, improvements in mean International Prostate Symptom Score (IPSS), Quality of Life (QoL), prostatic volume (total volume and transition zone), and peak urinary flow () were 9.8 points, 2.3 points, 28.1 mL, 17.8 mL, and 4.5 mL/s, respectively. Clinical success was obtained in seven of nine patients (78%). Patients in the microsphere group showed greater improvement in IPSS, QoL, prostatic volume, and compared to patients in the nonspherical PVA particle group. However, significant difference was noted only in the prostatic volume. Conclusion. PAE is a feasible, effective, and safe treatment option for BPH with LUTS. Use of microspheres showed greater prostatic volume reduction compared to nonspherical PVA particles.