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BioMed Research International
Volume 2017, Article ID 8923819, 5 pages
Clinical Study

The Effect of LASIK Procedure on Peripapillary Retinal Nerve Fiber Layer and Macular Ganglion Cell-Inner Plexiform Layer Thickness in Myopic Eyes

1Medical Faculty, Department of Ophthalmology, University of Nis, Nis, Serbia
2Ophthalmology Clinic, Clinical Center Nis, Nis, Serbia
3Medical Faculty, Department of Ophthalmology, University of Belgrade, Belgrade, Serbia
4Faculty of Medicine, Institute of Vision and Optics (IVO), Vardinoyiannion Eye Institute of Crete, University of Crete, Heraklion, Crete, Greece
5Eye Clinic Maja, Nis, Serbia
6Faculty of Medical Science, Department of Ophthalmology, University of Kragujevac, Kragujevac, Serbia
7FASPER, University of Belgrade, Belgrade, Serbia
8Jules Gonin Eye Hospital, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland

Correspondence should be addressed to Vesna Jaksic; ten.rotkev@ciskajv

Received 22 May 2017; Accepted 24 July 2017; Published 5 September 2017

Academic Editor: Atsushi Mizota

Copyright © 2017 Maja Zivkovic et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Purpose. To evaluate the effect of applied suction during microkeratome-assisted laser in situ keratomileusis (LASIK) procedure on peripapillary retinal nerve fiber layer (RNFL) thickness as well as macular ganglion cell-inner plexiform layer (GC-IPL) thickness. Methods. 89 patients (124 eyes) with established myopia range from −3.0 to −8.0 diopters and no associated ocular diseases were included in this study. RNFL and GC-IPL thickness measurements were performed by spectral domain optical coherence tomography (SD OCT) one day before LASIK and at 1 and 6 months postoperatively. Results. Mean RNFL thickness prior to LASIK was μm while the first month and the sixth month postoperatively were μm and μm, respectively. Comparing results, there is no significant difference between baseline, one month, and six months postoperatively for mean RNFL (). Mean GC-IPL thickness was μm preoperatively with no significant difference during the follow-up period (μm versus μm; ). Conclusion. RNFL and GC-IPL complex thickness remained unaffected following LASIK intervention.