BioMed Research International / 2017 / Article / Tab 2 / Research Article
Focal Defects of the Knee Articular Surface: Evidence of a Regenerative Potential Pattern in Osteochondritis Dissecans and Degenerative Lesions Table 2 Histological score.
Cartilage compartment (Mankin score [24 ]) Cartilage structure Normal 0 Surface irregularities 1 Pannus and Surface irregularities 2 Clefts to transitional zone 3 Clefts to radial zone 4 Clefts to calcified zone 5 Complete disorganization 6 Cells Normal 0 Diffuse hypercellularity 1 Cloning 2 Hypocellularity 3 Safranin O staining Normal 0 Slight reduction 1 Moderate reduction 2 Severe Reduction 3 No dye noted 4 Tidemark integrity Intact 0 Crossed by blood vessels 1 Crossed by fibrous tissues 2 Duplication 3 Bone compartment Bone plate integrity Normal 0 Decreased plate thickness 1 Increased plate thickness 2 Trabecular bone integrity Normal 0 Decreased trabecular thickness 1 Increased trabecular thickness 2 Bone cells Normal cellularity 0 Hypercellularity 1 Hypocellularity 2 Empty lacunae ≥30% 3 Bone marrow (BM) integrity Normal 0 BM + with vascular component 1 BM + vascular + inflammatory cells 2 BM + vascular component + inflammatory cells + fibrous tissues ≥30% 3
Cartilage maximal score 16 (low <4; medium 5–9; high >9 score); bone maximal score 10 (low <3; medium 4–7; high >7 score); total score 26 (normal = 0).
