The Phytoestrogen Genistein Produces Similar Effects as 17β-Estradiol on Anxiety-Like Behavior in Rats at 12 Weeks after Ovariectomy

Table 2

Effects of tamoxifen, 17β-estradiol, and genistein on crossing, grooming, and rearing in the locomotor activity test.

Groups	Crossing (n)	Grooming (s)	Rearing (s)
Vehicle	±	±	±
T	±	±	±
17β-E2	±
17β-E2-T	±	±	±
Genistein	±
Genistein-T	±	±	±

, versus Vehicle, T, 17β-E2-T, and Genistein-T. One-way ANOVA followed by Student-Newman-Keuls post hoc test. T, 5 mg/kg tamoxifen; 17β-E2, 0.09 mg/kg 17β-estradiol; Genistein 0.09 mg/kg.