Research Article

Clinical Implications of Oscillatory Lung Function during Methacholine Bronchoprovocation Testing of Preschool Children

Table 4

IOS values according to the results of Rrs5 and Xrs5 prior to the development of airway obstruction.

Rrs5Xrs5
Positive Negative valuePositive Negative p Value

Baseline value (SD)1.07 1.34 (0.21)<0.001 (0.11)0.56 (0.11)<0.001
 Change of -score (SD) (1.04) (1.24)<0.0010.41 (0.55) (0.49)<0.001
Stop Abs change value (SD)0.51 (0.16)0.19 (0.10)<0.001 (0.15) (0.11)0.003
-score (SD) (1.65) (1.35)0.336 (1.25) (0.99)0.779
 % Change (SD)44.16 (7.88)<0.001 (36.3) (15.0)0.003
 SD-index (SD)   (1.07)<0.001 (2.33) (1.67)<0.001

Positive response refers to a change of 30% or more in Rrs5 prior to development of airway obstruction (Condition ). Negative response refers to no change in Rrs5. For Xrs5, a positive response refers to a change of 80% or more. The SD-index was obtained by dividing the change from baseline values by SDw, which was calculated by dividing the difference between the mean values of the 1st and 2nd measurements by √2; Rrs5, resistance at 5 Hz; Xrs5, reactance at 5 Hz; SD, standard deviation; Abs, absolute.