Chemopreventive Effects of Germinated Rough Rice Crude Extract in Inhibiting Azoxymethane-Induced Aberrant Crypt Foci Formation in Sprague-Dawley Rats

Table 3

The effect of germination of rough rice (GRR) crude extract on the incident of ACF in rat colon induced with azoxymethane (AOM).

Group	Treatment	1 crypt	2 crypts	3 crypts	4 or more crypts	Total number of ACF/colon
1	AOM alone	15.67 ± 2.08	11.67 ± 3.51	8.33 ± 1.53	11 ± 1.73	46.67 ± 2.52
2	AOM + 500 mg/kg	13 ± 1	7.67 ± 1.15	8 ± 2.65	10 ± 1.73	38.67 ± 2.52
3	AOM + 1000 mg/kg	8.67 ± 1.53	8 ± 2	5.67 ± 2.08	7.67 ± 1.15	30 ± 1.73
4	AOM + 2000 mg/kg	8 ± 2	7 ± 1.73	5.67 ± 0.58	5.67 ± 2.89	26.33 ± 2.08
5	Normal	0	0	0	0	0

Each value is expressed as mean ± SD (). Different capital letters show significant difference in each row and different small letters show significant difference in each column as determined by Tukey’s multiple range test ().