Association between NLPR1, NLPR3, and P2X7R Gene Polymorphisms with Partial Seizures
Table 6
Genotypic and allelic distribution of the P2RX7 gene between all patients and controls .
SNP
Genotype/allele
Case (%)
Control (%)
value
OR (95% CI)
value
rs3751143
TT
94 (57.7)
127 (63.2)
0.451 (1.592)
1.00
Referent
TG
59 (36.2)
66 (32.8)
0.828 (0.533–1.287)
0.401
GG
10 (6.1)
8 (4.0)
0.592 (0.225–1.558)
0.288
GT + GG
69 (42.3)
74 (36.8)
0.284 (1.148)
0.794 (0.520–1.211)
0.284
T
247 (75.8)
320 (79.6)
0.215 (1.537)
1.00
Referent
G
79 (24.2)
82 (20.4)
0.801 (0.564–1.138)
0.215
rs208294
AA
58 (35.6)
69 (34.3)
0.741 (0.599)
1.00
Referent
AG
83 (50.9)
99 (49.3)
1.003 (0.636–1.580)
0.991
GG
22 (13.5)
33 (16.4)
1.261 (0.663–2.397)
0.480
AG + GG
105 (64.4)
132 (65.7)
0.830 (0.062)
1.057 (0.685–1.630)
0.803
A
199 (61.0)
237 (59.0)
0.568 (0.327)
1.00
Referent
G
127 (39.0)
165 (41.0)
1.091 (0.809–1.470)
0.568
CI, confidence interval; OR, odds ratio. value for genotype and allele frequencies in cases and controls using 2-sided test. values adjusted by age and gender using logistic regression.
