BioMed Research International / 2017 / Article / Tab 1

Research Article

Insulin Resistance in Early Rheumatoid Arthritis Is Associated with Low Appendicular Lean Mass

Table 1

Characteristics of the study groups.

GenderTotal
Male Female
Early RA
26
Control group
148
Early RA
66
Control group
173
Early RA
92
Control group
321

Female, (%)66 (71.7)173 (53.9)
Age, years56 (3)45 (1)51 (2)50 (1)52 (2)48 (1)
Smoking
 Ever, (%)16 (64.0)29 (19.6)14 (21.5)36 (20.8)30 (33.3)65 (20.2)
CRP, mg/l21.7 (5.1)1.8 (0.2)7.9 (1.4)2.5 (0.3)11.8 (1.9)2.2 (0.2)
TNF-alpha, pg/ml4.0 (0.6)2.1 (0.2)2.3 (0.2)1.8 (0.1)2.8 (0.2)2.0 (0.1)
IL-6, pg/ml27.8 (8.3)1.4 (0.9)12.4 (3.7)0.3 (0.1)16.7 (3.6)0.8 (0.4)
Glucose, mmol/l5.3 (0.1)5.4 (0.1)5.3 (0.1)5.2 (0.1)5.3 (0.1)5.3 (0.0)
Insulin, mU/l15.3 (1.9)7.2 (0.4)13.2 (2.2)6.9 (0.4)13.8 (1.6)7.0 (0.3)
HOMA-IR score, units3.6 (0.4)1.8 (0.1)3.1 (0.5)1.7 (0.1)3.2 (0.4)1.7 (0.1)
Insulin-resistant, (%)19 (73.1)41 (27.7)32 (48.5)39 (22.5)51 (55.4)80 (24.9)
BMI, Kg/m226.4 (0.9)27.4 (0.4)27.5 (0.8)27.0 (0.5)27.2 (0.6)27.2 (0.3)
BMI group
 Normal, (%)11 (42.3)50 (33.8)26 (39.4)73 (42.2)37 (40.2)123 (38.3)
 Overweight, (%)10 (38.5)55 (37.2)21 (31.8)50 (28.9)31 (33.7)105 (32.7)
 Obese, (%)5 (19.2)43 (29.1)19 (28.8)50 (28.9)24 (26.1)93 (29.0)
Fat mass, Kg21.9 (1.9)23.8 (0.9)29.3 (1.3)28.5 (0.9)27.2 (1.1)26.3 (0.6)
FMI, Kg/m27.3 (0.7)7.4 (0.3)11.2 (0.6)10.6 (0.3)10.1 (0.5)9.1 (0.2)
FFM, Kg58.2 (1.2)65.5 (0.7)43.0 (0.7)44.6 (0.4)47.3 (0.9)54.2 (0.7)
FFMI, Kg/m219.1 (0.3)20.3 (0.2)16.2 (0.2)16.5 (0.2)17.0 (0.2)18.2 (0.2)
ALM, Kg23.9 (0.6)28.4 (0.3)17.1 (0.3)18.0 (0.2)19.0 (0.4)22.8 (0.3)
ALMI, Kg/BMI0.93 (0.04)1.05 (0.01)0.64 (0.02)0.69 (0.01)0.72 (0.02)0.86 (0.01)

Values represent the mean ± SE if not stated otherwise. Statistically significant differences are shown in boldface type (). HOMA-IR: homeostatic model assessment for insulin resistance; BMI: body mass index; FMI: fat mass index (fat mass Kg/height m2); FFM: fat-free mass; FFMI: fat-free mass index (fat-free mass/height m2); ALM: appendicular lean mass; ALMI: appendicular lean mass index (appendicular lean mass Kg/BMI).

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