| First author (year) | Sample size (male/female) | Random method | Treatment | Control | Frequency | Acupoints | Place | Time | Course | Outcome measurements | Follow-Up | Safety | Assessment of bias |
| Cao (2009) | 60 (34/26) | 60 (31/29) | The random number table | AC | Estazolam | Per day | GV20, H7, EX-HN1, SP6, B62, K6 | Guangdong | >1 m | Not reported | HAMD; PSQI | Not reported | Not reported | +; ?; −; +; −; +; −; ? | Feng (2011) | 40 (26/14) | 40 (27/13) | The random number table | AC | Fluoxetine | Per day | ST40, SP9, SP10, SP6, EX-HN3, DU20, EX-HN1, PC6, TF4 | Beijing | >1 m | 30 d | HAMD; PSQI; SDS | Not reported | Not reported | +; −; −; −; +; −; ? | He (2010) | 30 (11/19) | 30 (7/23) | The random number table | AC | Estazolam | Per day | GV20, GV17, G19, ST36, P6, H7, SP6, LIV3 | Guangdong | >1 m | 4 w | SAS; SDS; PSQI | Not reported | Not reported | +; −; −; −; +; −; ? | Ji (2013) | 93 (39/54) | 94 (41/53) | Visiting sequence | AC | Trazodone | Per day | H7, GV20, GV29, LI4, LIV3 | Jiangsu | >1 m | 20 d | PSQI; HAMD; ASBERG; effective rate | Not reported | Y | −; −; −; −; +; −; ? | Liu (2009) | 30 | 30 | The random number table | AC | Clonazepam | Per day | Sishenzhen, P6, SP6, Dingshenzhen, B62, K2 | Guangdong | >1 m | 18 d | PSQI; SDS; effective rate | 1–3 m | Not reported | +; −; −; −; +; −; ? | Luo (2010) | 33 (10/23) | 33 (11/21) | Computer software SPSS | AC | Trazodone and Mesyre | Per day | H7, GV20, GV29, LI4, LIV3 | Jiangsu | 2 m~3 y | 4 w | PSQI; SDS; SERS | Not reported | Y | +; −; −; −; +; +; ? | Song (2007) | 60 | 60 | Computer software | AC | Estazolam | 5 times, one week | GV20, EX-HN1 | Beijing | 2 m~2 y | 4 w | SDS; PSQI; SERS | No | Y | +; −; −; +; +; +; ? | Song (2013) | 60 | 60 | The random number table | AC | Fluoxetine | Per day | GV20, GV24, B62, K2 | Hebei | 1–6 m | 4 w | HAMD; PSQI; effective rate; SERS | Not reported | Y | +; −; −; −; +; +; ? | Wang (2004) | 34 (22/12) | 30 (17/13) | The random number table | AC | Estazolam | 5 times, one week | H7, P6, CV12, ST36, K3 | Beijing | >1 m | 4 w | HAMD; PSQI; effective rate | Not reported | Y | +; −; −; −; +; −; ? | Wang (2015) | 45 (20/25) | 45 (16/29) | Treatment sequence | AC | Mirtazapine | Per day | SP6, H7, EX-HN1 | Jilin | >1 m | 2 m | HAMD; PSQI; effective rate | Not reported | Not reported | −; −; −; −; ?; −; ? | Ye (2014) | 40 (9/31) | 40 (12/28) | Not reported | AC | Mirtazapine | Per day | H7, SP6, GV29, LIV3, GB34, ST36, P5 | Shanghai | >3 m | 3 m | HAMD; PSQI; effective rate | Not reported | Not reported | ?; −; −; −; +; +; ? | Yeung (2011) | 26 (6/20) | 52 (10/42) | Software | EA | Sham AC and placebo AC | 3 times, one week | EX-HN3, GV20, Ear Shenmen, EX-HN1 | Hong Kong | >1 m | 21 d | PSQI; HAMD; ISI | 1 m | Y | +; +; +; +; +; +; ? | Ka-Fai Chung (2015) | 60 (14/46) | 90 (17/73) | Software | EA | Sham AC and placebo AC | 3 times, one week | EX-HN3, GV20, and Ear Shenmen, EX-HN1, EX | Hong Kong | >1 m | 21 d | PSQI; HAMD; ISI | 1 m | Y | +; +; +; +; +; +; ? | Wang (2006) | 23 (12/11) | 22 (10/12) | Treatment date | AC combined with antidepression drugs | Antidepression drugs | Per day | GV24, GV20, GV14, DU11, CV9 | Jiang Su | Not reported | 4 w | HAMD; PSQI | Not reported | Not reported | −; −; −; ?; ?; −; ? | Feng (2006) | 52 (38/14) | 52 (34/18) | Not reported | AC combined with ultraviolet oral fluoxetine and alprazolam | Fluoxetine and alprazolam | Per day | P6, K3, H7, CV12, ST36 | He Nan | >1 m | 20 d | HAMD; PSQI | 3 m | Not reported | ?; −; −; −; −; −; ? | Li (2005) | 26 (10/16) | 24 (9/15) | Not reported | AC combined with fluoxetine | Fluoxetine | Per day | EX-HN22, GV20, GV29 | Bei Jing | 2 m~22 y | 28 d | Effective rate | Not reported | Not reported | ?; −; −; −; +; −; ? | Liu (2010) | 30 | 30 | Not reported | AC combined with Wuling Capsule | Wuling Capsule | Per day | GV20, GV29, H7, GV26, EX-HN1 | He Nan | 1~12 y | 4 w | HAMD; PSQI; TESS | Not reported | Not reported | ?; −; −; −; +; −; ? | Zhang (2015) | 30 (18/12) | 30 (23/7) | Not reported | AC combined with Guipi decoction | Mirtazapine | Per day | H7, GV29, GV20, EX-HN22, ST36, SP6, P6 | Guang Dong | >1 m | 4 w | SDS; PSQI | Not reported | Not reported | ?; −; −; −; +; −; ? |
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