Evaluation of Epigallocatechin-3-gallate Modified Collagen Membrane and Concerns on Schwann Cells

Figure 3

Gene expression of BDGF (a) and NGF (b) in RSC96 cells incubated on EGCG-treated collagen membranes for 7 and 14 days measured by RT-PCR. Quantification of released BDGF (c) and NGF (d) for 7 and 14 days produced by RSC96 cells measured by ELISA. Significant difference compared to control group (Col) at < 0.05, < 0.01, and < 0.001. According to ELISA and RT-PCR, neurotrophic factors produced by RSC96 cells were significantly increased after implantation of EGCG-modified collagen membranes.

(a)

(b)

(c)

(d)