BioMed Research International / 2017 / Article / Tab 4

Review Article

Antifatigue Functions and Mechanisms of Edible and Medicinal Mushrooms

Table 4

Other bioactive constituents (than polysaccharides) and possible antifatigue mechanisms of some important mushrooms.

FamilySpeciesActive componentsMechanism for antifatigueRef.

CordycipitaceaeCordyceps sinensisPolypeptideImproves cardiovascular function through vasodilation effect;
Improves energy state of liver.
MannitolFree radical scavenging activity.[82]
CordycepinFree radical scavenging activity.[83]

GanodermataceaeGanoderma lucidumProtein of LZ-8Improves T lymphocytes response to cytokines;[84]
Peptide with amino acids rich in phenylalanine, aspartic acid, proline, histidine, and isoleucineAntioxidant activity.[11]
TriterpenoidsStrong antioxidant activity;
Regulates body testosterone level.
[62, 85]
AdenosineInhibitory platelet aggregation to enhance blood circulation.[86]

AgaricaceaeAgaricus bisporusGallic acid, flavonoid, ascorbic acid, and phenolic compoundsAntioxidant activity.[87, 88]

TricholomataceaeTricholoma matsutakePeptideImproves cardiovascular function by antihypertensive action;
Free radical scavenging activity.

MeripilaceaeGrifola gargalAdenosinePromotes glucose uptake in skeletal muscle cells.[90]

FomitopsidaceaeAntrodia cinnamomeaErgostane and lanostane skeleton triterpenoidsSignificantly improves muscular function.[12]

HymenochaetaceaeInonotus obliquusPolyphenol of inonoblins and phelligridinsSignificant DPPH radical scavenging and moderate superoxide anion scavenging activities.[44]