Antifatigue Functions and Mechanisms of Edible and Medicinal Mushrooms

Table 4

Other bioactive constituents (than polysaccharides) and possible antifatigue mechanisms of some important mushrooms.

Family	Species	Active components	Mechanism for antifatigue	Ref.
Cordycipitaceae	Cordyceps sinensis	Polypeptide	Improves cardiovascular function through vasodilation effect; Improves energy state of liver.	[53]
		Mannitol	Free radical scavenging activity.	[82]
		Cordycepin	Free radical scavenging activity.	[83]
Ganodermataceae	Ganoderma lucidum	Protein of LZ-8	Improves T lymphocytes response to cytokines;	[84]
		Peptide with amino acids rich in phenylalanine, aspartic acid, proline, histidine, and isoleucine	Antioxidant activity.	[11]
		Triterpenoids	Strong antioxidant activity; Regulates body testosterone level.	[62, 85]
		Adenosine	Inhibitory platelet aggregation to enhance blood circulation.	[86]
Agaricaceae	Agaricus bisporus	Gallic acid, flavonoid, ascorbic acid, and phenolic compounds	Antioxidant activity.	[87, 88]
Tricholomataceae	Tricholoma matsutake	Peptide	Improves cardiovascular function by antihypertensive action; Free radical scavenging activity.	[89]
Meripilaceae	Grifola gargal	Adenosine	Promotes glucose uptake in skeletal muscle cells.	[90]
Fomitopsidaceae	Antrodia cinnamomea	Ergostane and lanostane skeleton triterpenoids	Significantly improves muscular function.	[12]
Hymenochaetaceae	Inonotus obliquus	Polyphenol of inonoblins and phelligridins	Significant DPPH radical scavenging and moderate superoxide anion scavenging activities.	[44]