Local Anesthetics, Procaine, Lidocaine, and Mepivacaine Show Vasodilatation but No Type 1 Allergy: A Double-Blind, Placebo-Controlled Study
Table 2
Characteristics of patients receiving different LAs. LAs used for intracutaneous tests were procaine, lidocaine, mepivacaine, and saline solution (NaCl). Evaluation of 340 injections from 177 patients.
Procaine 1%
Lidocaine 0.5%
Mepivacaine 1%
NaCl 0.9%
All,
Difference
Female
90.3
90.6
90.2
87.8
90.2
n.s.
Age (years)
49.4 ± 13.0
50.4 ± 13.5
49.6 ± 14.5
48.8 ± 14.4
49.7 ± 13.5
n.s.
BMI (kg/m2)
23.0 ± 3.8
23.0 ± 3.7
22.7 ± 3.3
23.0 ± 3.5
22.9 ± 3.6
n.s.
Previously treated with LA
98.3
97.7
100
100
98.7
n.s.
History of drug allergy (antibiotics and others, without LAs)
10.3
11.4
9.7
9.6
37 (10.9)
n.s.
History of LA allergy
(0.12)
n.s.
Allergy history: multiple specifications were possible.
