Naturally Occurring Resistance-Associated Variants to Hepatitis C Virus Direct-Acting Antiviral Agents in Treatment-Naive HCV Genotype 6a-Infected Patients

Table 1

Characteristics of HCV 6a-infected patients with mutations.

Characteristics	HCV-6a	HCV-1b
	88	69
Age (years)	33.6 ± 14.2	38.5 ± 13.2	0.771	0.033
Male (%)	55 (62.5%)	43 (62.3%)	0.001	1.000
ALT (U/L)	62.5 (10, 425)	54.5 (17, 285)		0.772
AST (U/L)	44 (11, 258)	41 (18–164)		0.414
ALB (g/l)	43.5 ± 3.4	44.7 ± 3.3	0.355	0.054
PLT (×109)	206.3 ± 83.8	192.4 ± 69.0	0.583	0.227
Hb (g/l)	137.6 ± 18.4	147.5 ± 16.7	0.233	0.001
BMI (kg/m2)	21.8 ± 3.9	21.9 ± 2.8	0.039	0.964
HCV RNA (IU/ml log10)	6.9 ± 0.7	7.1 ± 0.7	0.585	0.360
Liver cirrhosis	0	0
RVR	75.0% (66/88)	65.2% (45/69)	1.787	0.217
EVR	78.4% (69/88)	72.4% (50/69)	0.745	0.454
SVR	83.0% (73/88)	78.3% (54/69)	0.551	0.541