Unexpected Genetic Cause in Two Female Siblings with High Myopia and Reduced Visual Acuity

Figure 1

Pedigree of family 2837. The index case and all tested members of the family are labelled (DNA). The pedigree includes several consanguinity loops giving rise to two further affected individuals in the branch of the mother. Double line: consanguineous marriage. Further symbol definitions as given in the figure. Diamond = unknown sex, circle = female, square = male, open symbols = unaffected, number in symbols = number of individuals.