Research Article
Discovering Associations of Adverse Events with Pharmacotherapy in Patients with Non-Small Cell Lung Cancer Using Modified Apriori Algorithm
Table 4
The number of patients with different types and levels of adverse events.
| | SOC | Adverse event | 1 | 2 | 3 | 4 | Grand total | Percentage (%) |
| | Blood and lymphatic system disorders | Anemia | 6076 | 2439 | 512 | | 6426 | 38.88% | | Investigations | Activated partial thromboplastin time prolonged | 2203 | 59 | 8 | | 2222 | 13.44% | | Investigations | Alanine aminotransferase increased | 4567 | 498 | 201 | 20 | 4762 | 28.81% | | Investigations | Alkaline phosphatase increased | 1250 | 132 | 28 | | 1283 | 7.76% | | Investigations | Aspartate aminotransferase increased | 3230 | 249 | 131 | 24 | 3366 | 20.37% | | Investigations | Blood bilirubin increased | 3777 | 1083 | 76 | 8 | 4165 | 25.20% | | Investigations | Cholesterol high | 4430 | 242 | 7 | 4 | 4459 | 26.98% | | Investigations | CPK increased | 5023 | 3006 | 2421 | 455 | 8415 | 50.92% | | Investigations | Creatinine increased | 1091 | 110 | 7 | 2 | 1135 | 6.87% | | Investigations | Fibrinogen decreased | 413 | 78 | 19 | 6 | 475 | 2.87% | | Investigations | GGT increased | 4896 | 1283 | 427 | 21 | 5286 | 31.98% | | Investigations | Hemoglobin increased | 3577 | 157 | 9 | | 3603 | 21.80% | | Investigations | Lymphocyte count decreased | 292 | 188 | 68 | 8 | 362 | 2.19% | | Investigations | Neutrophil count decreased | 3616 | 2133 | 1241 | 485 | 4364 | 26.41% | | Investigations | Platelet count decreased | 1487 | 795 | 316 | 97 | 1738 | 10.52% | | Investigations | White blood cell decreased | 4143 | 2364 | 1195 | 252 | 5134 | 31.06% | | Metabolism and nutrition disorders | Hypercalcemia | 646 | 22 | 18 | 9 | 669 | 4.05% | | Metabolism and nutrition disorders | Hyperglycemia | 5832 | 1844 | 362 | 393 | 6549 | 39.63% | | Metabolism and nutrition disorders | Hypermagnesemia | 1285 | | 87 | | 1348 | 8.16% | | Metabolism and nutrition disorders | Hypertriglyceridemia | 6532 | 1117 | 361 | 179 | 6849 | 41.44% | | Metabolism and nutrition disorders | Hyperuricemia | 3414 | | | 133 | 3438 | 20.80% | | Metabolism and nutrition disorders | Hypoalbuminemia | 6183 | 1 | 1 | | 6183 | 37.41% | | Metabolism and nutrition disorders | Hypocalcemia | 7598 | 3332 | 154 | 21 | 8915 | 53.94% | | Metabolism and nutrition disorders | Hypoglycemia | 254 | 16 | 2 | 1 | 269 | 1.63% | | Metabolism and nutrition disorders | Hypomagnesemia | 396 | 9 | 5 | | 404 | 2.44% | | Metabolism and nutrition disorders | Hyponatremia | 85 | | 32 | 8 | 115 | 0.70% | | Metabolism and nutrition disorders | Hypophosphatemia | 2328 | 2470 | 639 | 15 | 4384 | 26.53% | | Renal and urinary disorders | Proteinuria | 673 | 47 | | | 707 | 4.28% |
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