Cisplatin-Induced Rodent Model of Kidney Injury: Characteristics and Challenges

Table 9

Surface markers of inflammatory cells in cisplatin rodent model.

Surface marker	Inflammatory cells that express surface marker	Ref.
CD45^+	pan-leukocyte marker	[162]
CD19^+ (CD79α)	marker of B cells	[163]
CD3^+	marker of T cells	[163]
F4/80^+	canonical marker of macrophages, monocytes	[73]
CD11c^+	canonical marker of DC, recently also macrophages, activated CD8+ T cells, plasma B cell blasts, NK	[66, 73, 164]
CD14^+	monocytes, macrophages, dendritic cells, neutrophils	[165]
CD11b^+	macrophages, monocytes, neutrophils, dendritic cells	[73]
CD11b^+CD27^+	NK (immature, mature)	[166]
CD49b^+	pan-NK marker,; small subset of CD8^+ T cells, platelets	[68]
F4/80^+CD11c^-CD206^+	macrophages M2	[167]
F4/80^+CD11c^+	macrophages M1	[167]
F4/80^-CD11c^+	dendritic cells	[167]
GR-1^+	neutrophils, monocytes	[73]
GR-1^+ CD11b^+ CD11c^+	monocyte-derived proinflammatory DC	[73]
GR-1^+ CD11b^+ CD11c^-	neutrophils, monocytes	[73]
7/4^+	monocytes, neutrophils	[73]
Ly6G^+	neutrophils	[73]
7/4^+Ly6G^-	monocytes	[73]

DC: dendritic cells; NK: natural killer cells