Role of MAPKs in HSP70’s Protection against Heat Stress-Induced Injury in Rat Small Intestine

Figure 2

Effects of HSP70 inhibition on rectal temperature (a) and serum cortisol level (b) of heat stressed rats. The experiment lasted for 14 days with daily 50 min of heat stress treatment (43°C) for the HS and HQ groups. Rats of HQ group were intragastrically given 0.5 mL quercetin solution (50 mg/kg body weight) before the heat stress treatment. (a) Rectal temperature was recorded on days 1, 7, and 14 of heat stress. (b) Serum cortisol levels on days 7 and 14 of heat stress were determined using a radioimmunoassay. Data are shown as mean ± standard error of mean (SEM) (n=8). The values with different letters (A, B) are significantly different (P<0.05). CON: control; HS: heat stress; HQ: heat stress + quercetin.

(a)

(b)