Influence of Adalimumab on the Expression Profile of Genes Associated with the Histaminergic System in the Skin Fibroblasts In Vitro

Table 4

The changes of the mRNA expression in cells treated with adalimumab.

ID	Gene name	Encoded protein name	Group	Change
201557_at	VAMP2	Vesicle associated membrane protein 2	2 h versus C	Up
204112_s_at	HNMT	Histamine N-methyltransferase	2 h versus C	Up
204639_at	ADA	Adenosine deaminase	2 h versus C	Up
205579_at	HRH1	Histamine receptor H1	2 h versus C	Up
205580_s_at	HRH1	Histamine receptor H1	2 h versus C	Up
209190_s_at	DIAPH1	Diaphanous related formin 1	2 h versus C	Down
211732_x_at	HNMT	Histamine N-methyltransferase	2 h versus C	Up
205421_at	SLC22A3	Solute carrier family 22 member 3	8 h versus C	Up
204463_s_at	EDNRA	Endothelin receptor type A	8 h versus K i 2 h versus C	Up/down
204464_s_at	EDNRA	Endothelin receptor type A	8 h versus K i 2 h versus C	Up/down
218995_s_at	EDN1	Endothelin 1	8 h versus K i 2 h versus C	Up/up
205329_s_at	SNX4	Sorting nexin 4	24 h versus C	Up
206678_at	GABRA1	Gamma-aminobutyric acid (GABA) A receptor, alpha 1	24 h versus C	Down
211624_s_at	DRD2	Dopamine receptor D2	24 h versus C	Down
202625_at	LYN	LYN proto-oncogene	24 h versus C	Up