Influence of Adalimumab on the Expression Profile of Genes Associated with the Histaminergic System in the Skin Fibroblasts In Vitro

Table 5

The miRNA microarray analysis of NHDF cells treated with adalimumab versus control group.

Compared groups	ID	Name	FC	Change	Gene	SVR score
2 h versus C	hsa-miR-1231_st	hsa-mir-1231	2,24	Up	EDNRA	−0,2007
2 h versus C	hsa-miR-1275_st	hsa-mir-1275	−2,39	down	ADA	N/A
					HRH1	−0,5925
					EDN1	−0,8504, −0,6048
					DIAPH1	−0,0025
					VAMP2	−0,2280
2 h versus C	hsa-miR-143_st	hsa-mir-143	2,21	Up	DIAPH1	−0,1193
2 h versus C	hsa-miR-16_st	hsa-miR-16	2,17	Up	EDNRA	−0,0062, −0,0299
2 h versus C	hsa-miR-1909-star_st	hsa-mir-1909	2,86	Up	EDN1	−0,2846
					DIAPH1	−0,4198
					VAMP2	−0,2332
2 h versus C	hsa-miR-196a_st	hsa-miR-196a	3,13	Up	EDN1	−0,384
2 h versus C	hsa-miR-199a-5p_st	hsa-miR-199a-5p	3,49	Up	DIAPH1	−0,0020
2 h versus C	hsa-miR-22_st	hsa-mir-22	3,04	Up	EDNRA	−0,0720
2 h versus C	hsa-miR-3162_st	hsa-mir-3162	2,07	Up	EDNRA	−0,0102
					VAMP2	−0,7142
2 h versus C	hsa-miR-34a_st	hsa-mir-34a	6,52	Up	HRH1	−0,0024, −0,0017
					VAMP2	−0,7881
2 h versus C	hsa-miR-382_st	hsa-mir-382	2,82	Up	HNMT	−0,3818
2 h versus C	hsa-miR-939_st	hsa-mir-939	2,17	Up	VAMP2	−0,9181
8 h versus C	hsa-miR-1909-star_st	hsa-mir-1909	2,79	Up	EDN1	−0,2846