Treatment of Punctate Inner Choroidopathy with Choroidal Neovascularization Using Corticosteroid and Intravitreal Ranibizumab

Figure 2

(a) Fundus photograph of the right eye of a 28-year-old female patient with PIC and CNV at initial presentation, showing yellow-white choroidal lesions and subfoveal hemorrhage. The logMAR BCVA was 0.7. (b) FAF image showed clear hypofluorescence of the lesions. (c) Late-phase FA image detected hyperfluorescent lesions. (d) Late-phase ICGA image detected areolar hyperfluorescence surrounding central dark spots. (e) OCT image demonstrated the presence of CNV and intraretinal fluid. (f) Fundus photograph at 12 months after initiating combined oral corticosteroid and ranibizumab therapy. The logMAR BCVA increased to 0. (g) FAF image showed less hypofluorescent lesions posttreatment. Note an evident resolution of the lesions compared with the first visit (white arrows). (h) Late-phase FA image showed less hyperfluorescent lesions after treatment (white arrows). (i) Late-phase ICGA image showed dramatic resolution and shrinkage of hypofluorescent lesions posttreatment (black arrows). (j) OCT showed the resolution of the CNV and intraretinal fluid.