Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2018 (2018), Article ID 1639623, 6 pages
https://doi.org/10.1155/2018/1639623
Research Article

Therapeutic Effect of Long-Term Epidural Block in Rats with Pregnancy Induced Hypertension

Department of Anesthesia, Shengjing Hospital of China Medical University, No. 36, Sanhao Street, Herping District, Shenyang 110004, China

Correspondence should be addressed to Youjing Dong

Received 12 September 2017; Revised 18 December 2017; Accepted 11 January 2018; Published 7 February 2018

Academic Editor: Kotaro Kitaya

Copyright © 2018 Nianjiao Han et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. Sibai, G. Dekker, and M. Kupferminc, “Pre-eclampsia,” The Lancet, vol. 365, no. 9461, pp. 785–799, 2005. View at Publisher · View at Google Scholar · View at Scopus
  2. R. A. Odegard, L. J. Vatten, S. T. Nilsen, K. A. Salvesen, and R. Austgulen, “Risk factors and clinical manifestations of pre-eclampsia,” International Journal of Obstetrics and Gynaecology, vol. 107, no. 11, pp. 1410–1416, 2015. View at Google Scholar
  3. S. J. Fisher, “Why is placentation abnormal in preeclampsia?” American Journal of Obstetrics and Gynecology, vol. 213, no. 4, p. S115, 2015. View at Google Scholar
  4. H. N. Moussa, S. E. Arian, and B. M. Sibai, “Management of hypertensive disorders in pregnancy,” Women's Health Journal (WHJ), vol. 10, no. 4, pp. 385–404, 2014. View at Publisher · View at Google Scholar · View at Scopus
  5. P. H. Andraweera, G. A. Dekker, J. A. Laurence, and C. T. Roberts, “Placental expression of VEGF family mRNA in adverse pregnancy outcomes,” Placenta, vol. 33, no. 6, pp. 467–472, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. Y. Ren, H. Wang, H. Qin et al., “Vascular endothelial growth factor expression in peripheral blood of patients with pregnancy induced hypertension syndrome and its clinical significance,” Pakistan Journal of Medical Sciences, vol. 30, no. 3, pp. 634–637, 2014. View at Publisher · View at Google Scholar · View at Scopus
  7. V. Tandon, S. Hiwale, D. Amle, T. Nagaria, and P. K. Patra, “Assessment of serum vascular endothelial growth factor levels in pregnancy-induced hypertension patients,” Journal of Pregnancy, vol. 2017, Article ID 3179670, 5 pages, 2017. View at Publisher · View at Google Scholar · View at Scopus
  8. M. L. Tjoa, R. J. Levine, and S. A. Karumanchi, “Angiogenic factors and preeclampsia,” Seminars in Nephrology, vol. 31, no. 1, pp. 33–46, 2011. View at Google Scholar
  9. F. Gerheuser and A. Roth, “Epidural anesthesia,” Der Anaesthesist, vol. 56, no. 5, pp. 499–526, 2007. View at Publisher · View at Google Scholar · View at Scopus
  10. R. J. Moraca, D. G. Sheldon, and R. C. Thirlby, “The role of epidural anesthesia and analgesia in surgical practice,” Annals of Surgery, vol. 238, no. 5, pp. 663–673, 2003. View at Publisher · View at Google Scholar
  11. W. Gyselaers, W. Mullens, K. Tomsin, T. Mesens, and L. Peeters, “What is the role of dysfunctional maternal venous hemodynamics in the pathophysiology of preeclampsia? An exciting new research question in obstetrics,” Ultrasound in Obstetrics and Gynecology, 129 pages, 2014. View at Google Scholar
  12. J. F. Ducray, T. Naicker, and J. Moodley, “Pilot study of comparative placental morphometry in pre-eclamptic and normotensive pregnancies suggests possible maladaptations of the fetal component of the placenta,” European Journal of Obstetrics & Gynecology and Reproductive Biology, vol. 156, no. 1, pp. 29–34, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. B. L. J. Li and J. F. Reckelhoff, “A model of preeclampsia in rats: the reduced uterine perfusion pressure (RUPP) model,” Ajp Heart and Circulatory Physiology, vol. 303, no. 1, pp. H1–H8, 2012. View at Publisher · View at Google Scholar
  14. S. Intapad, J. P. Warrington, F. T. Spradley et al., “Reduced uterine perfusion pressure induces hypertension in the pregnant mouse,” American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, vol. 307, no. 11, pp. R1353–R1357, 2014. View at Publisher · View at Google Scholar · View at Scopus
  15. M. H. Schenone, G. Mari, N. Schlabritz-Loutsevitch, and R. Ahokas, “Effects of selective reduced uterine perfusion pressure in pregnant rats,” American Journal of Obstetrics and Gynecology, vol. 36, no. 12, p. 1450, 2015. View at Google Scholar
  16. F. P. McCarthy, J. C. Kingdom, L. C. Kenny, and S. K. Walsh, “Animal models of preeclampsia; Uses and limitations,” Placenta, vol. 32, no. 6, pp. 413–419, 2011. View at Publisher · View at Google Scholar · View at Scopus
  17. O. Balta, A. Boztosun, K. Deveci et al., “Reduced uterine perfusion pressure model is not successful to mimic severe preeclampsia,” Placenta, vol. 32, no. 9, pp. 675–680, 2011. View at Publisher · View at Google Scholar · View at Scopus
  18. A. Salajegheh, Vascular Endothelial Growth Factor (VEGF), Springer International Publishing, Berlin, Germany, 2016.
  19. Y. Zhou, Y. Jiang, Y. Bai, J. Wen, and L. Chen, “Vascular endothelial growth factor plasma levels before and after treatment of retinopathy of prematurity with ranibizumab,” Graefe's Archive for Clinical and Experimental Ophthalmology, vol. 254, no. 1, pp. 31–36, 2016. View at Google Scholar
  20. S. S. Kalkunte, T. F. Mselle, W. E. Norris, C. R. Wira, C. L. Sentman, and S. Sharma, “Vascular endothelial growth factor C facilitates immune tolerance and endovascular activity of human uterine NK cells at the maternal-fetal interface,” The Journal of Immunology, vol. 182, no. 7, pp. 4085–4092, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. R. Tripathi, R. Ralhan, S. Saxena, S. Salhan, and G. Rath, “Soluble VEGFR-1 in pathophysiology of pregnancies complicated by hypertensive disorders: the Indian scenario,” Journal of Human Hypertension, vol. 27, no. 2, pp. 107–114, 2013. View at Publisher · View at Google Scholar · View at Scopus
  22. J. Wang, Y.-M. Tao, X.-Y. Cheng et al., “Vascular endothelial growth factor affects dendritic cell activity in hypertensive disorders of pregnancy,” Molecular Medicine Reports, vol. 12, no. 3, pp. 3781–3786, 2015. View at Publisher · View at Google Scholar · View at Scopus
  23. J. S. Gilbert, M. J. Ryan, B. B. Lamarca, M. Sedeek, S. R. Murphy, and J. P. Granger, “Pathophysiology of hypertension during preeclampsia: linking placental ischemia with endothelial dysfunction,” Hypertension, vol. 294, no. 2, pp. H541–H550, 2008. View at Publisher · View at Google Scholar · View at Scopus
  24. S. Venkatesha, M. Toporsian, C. Lam et al., “Soluble endoglin contributes to the pathogenesis of preeclampsia,” Nature Medicine, vol. 12, no. 6, pp. 642–649, 2006. View at Publisher · View at Google Scholar
  25. Z. Bian, C. Shixia, and T. Duan, “First-trimester maternal serum levels of sFLT1, PGF and ADMA predict preeclampsia,” PLoS ONE, vol. 10, no. 4, Article ID e0124684, 2015. View at Publisher · View at Google Scholar · View at Scopus
  26. J. P. Bridges, J. S. Gilbert, D. Colson et al., “Oxidative stress contributes to soluble fms-like tyrosine kinase-1 induced vascular dysfunction in pregnant rats,” American Journal of Hypertension, vol. 22, no. 5, pp. 564–568, 2009. View at Publisher · View at Google Scholar · View at Scopus
  27. S. R. Murphy, B. B. D. Lamarca, K. Cockrell, and J. P. Granger, “Role of endothelin in mediating soluble fms-like tyrosine kinase 1-induced hypertension in pregnant rats,” Hypertension, vol. 55, no. 2, pp. 394–398, 2010. View at Publisher · View at Google Scholar · View at Scopus
  28. F. T. Spradley, A. Y. Tan, W. S. Joo et al., “Placental growth factor administration abolishes placental ischemia-induced hypertension,” Hypertension, vol. 67, no. 4, pp. 740–747, 2016. View at Publisher · View at Google Scholar · View at Scopus
  29. N. G. Kemse, A. A. Kale, and S. R. Joshi, “Supplementation of maternal omega-3 fatty acids to pregnancy induced hypertension Wistar rats improves IL10 and VEGF levels,” Prostaglandins, Leukotrienes and Essential Fatty Acids, vol. 104, pp. 25–32, 2016. View at Publisher · View at Google Scholar · View at Scopus
  30. S. S. Jarvis, “Sympathetic activation during early pregnancy in humans,” The Journal of Physiology, vol. 590, no. 15, pp. 3535–3543, 2012. View at Publisher · View at Google Scholar · View at Scopus
  31. T. Fischer, H. P. Schobel, H. Frank, M. Andreae, K. T. M. Schneider, and K. Heusser, “Pregnancy-induced sympathetic overactivity: A precursor of preeclampsia,” European Journal of Clinical Investigation, vol. 34, no. 6, pp. 443–448, 2004. View at Publisher · View at Google Scholar · View at Scopus
  32. H. Freise, A. Meissner, S. Lauer et al., “Thoracic epidural analgesia with low concentration of bupivacaine induces thoracic and lumbar sympathetic block: a randomized, double-blind clinical trial,” Anesthesiology, vol. 109, no. 6, pp. 1107–1112, 2008. View at Publisher · View at Google Scholar · View at Scopus
  33. American College of Obstetricians and Gynecologists Obstetriciansgynecologists, “Hypertension in pregnancy. Report of the american college of obstetricians and gynecologists' task force on hypertension in pregnancy,” Obstetrics and Gynecology, vol. 122, no. 5, pp. 1122–1131, 2013. View at Publisher · View at Google Scholar · View at Scopus