Research Article

Effects of Hemodialysis on Thiol-Disulphide Homeostasis in Critically Ill Pediatric Patients with Acute Kidney Injury

Table 4

Comparison of thiol/disulphide homeostatic parameters between control and hemodialysis group.

Control
Median (Q1-Q3)
P
Pre-dialysis vs. Control
P
Post-dialysis vs.
Control

Native thiol (µmol/L)453.40 (431.90-464.30)0.00010.0001
Total thiol (µmol/L)482.00 (465.20-505.20)0.00010.0001
Disulphide (µmol/L)19.55 (14.95-21.70)0.00010.113
Disulphide/native thiol (%)4.15 (3.26-4.82)0.001 0.001
Disulphide/total thiol (%)3.83 (3.06-4.40)0.002 0.001
Native thiol/total thiol (%)92.33 (91.20-93.87)0.001 0.002

p<0.01 was considered significant for statistical analyses (Mann-Whitney U test).