Research Article
Effects of Hemodialysis on Thiol-Disulphide Homeostasis in Critically Ill Pediatric Patients with Acute Kidney Injury
Table 4
Comparison of thiol/disulphide homeostatic parameters between control and hemodialysis group.
| | Control Median (Q1-Q3) | P Pre-dialysis vs. Control | P Post-dialysis vs. Control |
| Native thiol (µmol/L) | 453.40 (431.90-464.30) | 0.0001 | 0.0001 | Total thiol (µmol/L) | 482.00 (465.20-505.20) | 0.0001 | 0.0001 | Disulphide (µmol/L) | 19.55 (14.95-21.70) | 0.0001 | 0.113 | Disulphide/native thiol (%) | 4.15 (3.26-4.82) | 0.001 | 0.001 | Disulphide/total thiol (%) | 3.83 (3.06-4.40) | 0.002 | 0.001 | Native thiol/total thiol (%) | 92.33 (91.20-93.87) | 0.001 | 0.002 |
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p<0.01 was considered significant for statistical analyses (Mann-Whitney U test). |