Splenic Doppler Resistive Index Variation Mirrors Cardiac Responsiveness and Systemic Hemodynamics upon Fluid Challenge Resuscitation in Postoperative Mechanically Ventilated Patients

Table 2

Hemodynamic findings before and after fluid challenge.

Parameters	FC Responders (n=30)			FC Non-responders (n=23)
	Before FC	After FC	P value	Before FC	After FC	P value
SV (mL)	45±14	59±18	<0.001	59±20	61±20	<0.001
SDRI	0.68±0.09	0.63±0.10	<0.001	0.64±0.09	0.62±0.09	0.006
CVP (mmHg)	12±4	12±4	0.554	14±4	13±4	0.200
MAP (mmHg)	76±10	75±8	0.609	73±12	72±8	0.933
PAOP (mmHg)	15±6	15±7	0.998	18±6	16±4	0.118
SVRI (dyne-sec/cm^−5/m^2)	2490±821	1935±575	<0.001	1928±617	1825±538	0.195
SVO2 (%)	58±9	63±7	0.012	63±7	63±6	0.686
cLac (mmol/L)	1.6±0.9	1.4±0.7	0.108	1.4±0.8	1.2±0.6	0.017

FC: Fluid challenge; SV: Stroke Volume; SDRI: Splenic Doppler resistive index; CVP: Central Venous Pressure; MAP: Mean artery pressure; PAOP: pulmonary artery occlusion pressure; SVRI: systemic vascular resistive index; SVO₂: mixed venous oxygen saturation; cLac: arterial lactate.