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BioMed Research International
Volume 2018, Article ID 2013671, 8 pages
Research Article

Evidence-Based Cutoff Threshold Values from Receiver Operating Characteristic Curve Analysis for Knee Osteoarthritis in the 50-Year-Old Korean Population: Analysis of Big Data from the National Health Insurance Sharing Service

Hyunseok Jee,1 Hae-Dong Lee,1,2,3,4 and Sae Yong Lee1,2,3,4

1Frontier Research Institute of Convergence Sports Science (FRICSS), Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea
2Integrated Sports Science Research Laboratory (ISSRL), Yonsei University, Seoul, Republic of Korea
3Department of Physical Education, College of Sciences in Education, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea
4Yonsei Institute of Sports Science and Exercise Medicine (YISSEM), Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea

Correspondence should be addressed to Sae Yong Lee;

Received 10 September 2017; Accepted 14 December 2017; Published 8 January 2018

Academic Editor: Danilo S. Bocalini

Copyright © 2018 Hyunseok Jee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We aimed to investigate the characteristics of patients with osteoarthritis (OA), using the data of all Koreans registered in the National Health Insurance Sharing Service Database (NHISS DB), and to provide ideal alternative cutoff thresholds for alleviating OA symptoms. Patients with OA (codes M17 and M17.1–M17.9 in the Korean Standard Classification of Disease and Causes of Death) were analyzed using SAS software. Optimal cutoff thresholds were determined using receiver operating characteristic curve analysis. The 50-year age group was the most OA pathogenic group (among 40~70 years, ). All exercise types affected the change of body mass index () and the sex difference in blood pressure (BP) (). All types of exercise positively affected the loss of waist circumference and the balance test (standing time on one leg in seconds) (). The cutoff threshold for the time in seconds from standing up from a chair to walking 3 m and returning to the same chair was 8.25 (80% sensitivity and 100% specificity). By using the exercise modalities, categorized multiple variables, and the cutoff threshold, an optimal alternative exercise program can be designed for alleviating OA symptoms in the 50-year age group.