In Vitro Cytotoxicity and In Vivo Antimammary Tumor Effects of the Hydroethanolic Extract of Acacia seyal (Mimosaceae) Stem Bark

Figure 4

Effects of A. seyal extract on microphotographs H&E 400x of liver, kidney, lung, and brain after 20 weeks of treatment. NOR = normal control treated with water; DMBA = DMBA control treated with water; AS + DMBA = animals treated with the A. seyal hydroethanolic aqueous extract at the doses of 50, 150, and 300 mg/kg. TAM + DMBA = animals treated with tamoxifen (3.3 mg/kg); all groups excepting the normal group (NOR) received an intragastric dose of DMBA at the dose of 80 mg/kg. Data are represented as mean ± SEM (). Data are represented as mean ± SEM (). Data are represented as mean ± SEM (). Vp = portal vein; H = hepatocyte; S = sinusoids; A = alveoli; Ba = aveolar bag; G = glomerulus; Dt = distal tube; Pt = proximal tube; Mi = microglia; Ne = neuron; Co = cortex.