Catestatin Induces Glucose Uptake and GLUT4 Trafficking in Adult Rat Cardiomyocytes

Figure 1

Cts stimulates glucose uptake. (a) Representative confocal images of adult rat cardiomyocytes incubated with the fluorescent glucose analog 2-NBDG in control, 100 nM Ins, 10 nM Cts, 10 nM Cts + 100 nM Wm. Pseudocolor images better show the fluorescence intensity variation. (b) Bar graph summarizing the experiments of fluorescent glucose uptake. The mean fluorescence intensity was 101.74±13.8 in control (n=72), 300.23±42.73 for Ins (n=30), 346.00±40.30 for Catestatin (n=52), and 137.12±19.63 for Cts+Wm (n=25). <0.001.

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