Research Article
lncRNA-MEG3 Suppresses the Proliferation and Invasion of Melanoma by Regulating CYLD Expression Mediated by Sponging miR-499-5p
Table 1
The association between clinical features and the MEG3 level in individuals with malignant melanoma.
| Clinicopathological finding | Patients | MEG3 | value | | High | Low |
| Age (years) | | | | | ≦60 | 25 | 13 | 12 | 0.753 | >60 | 17 | 8 | 9 | Sex | | | | | Male | 21 | 12 | 9 | 0.355 | Female | 21 | 9 | 12 | Tumor thickness (mm) | | | | | ≤1 | 16 | 12 | 4 | 0.011 | >1 | 26 | 9 | 17 | TNM classification | | | | | I + II | 17 | 13 | 4 | 0.005 | III + IV | 25 | 8 | 17 | Lymph node involvement | | | | | No | 19 | 16 | 3 | 0.000 | Yes | 23 | 5 | 18 | Distant metastasis | | | | | No | 27 | 19 | 8 | 0.000 | Yes | 15 | 2 | 13 |
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