Resveratrol Prevents Diabetic Cardiomyopathy by Increasing Nrf2 Expression and Transcriptional Activity

Table 3

Effects of resveratrol on cardiac dysfunction and heart rate in anesthetized DM mice (3 months).

Group	HR (beats/min)	LVID (mm)	IVS (mm)	LVPW (mm)	% EF (%)	% FS (%)
Control	496 ± 20	3.60 ± 0.13	0.72 ± 0.04	0.83 ± 0.10	90.46 ± 4.69	62.14 ± 4.49
Resveratrol	459 ± 24	3.59 ± 0.12	0.73 ± 0.03	0.86 ± 0.02	88.16 ± 4.64	58.76 ± 4.42
DM	440 ± 26	3.74 ± 0.16	0.75 ± 0.02	1.03 ± 0.04	68.22 ± 4.01	39.22 ± 3.18
DM/resveratrol	465 ± 24	3.62 ± 0.21	0.73 ± 0.01^#	0.9 ± 0.02^#	84.18 ± 3.03^#	49.10 ± 4.61^#

Data are presented as means ± SEM. LVID = LV end-diastolic diameter; LVPW = LV posterior wall; IVS = interventricular septum; FS = fractional shortening; EF = ejection fraction. versus control. versus DM group.