Research Article

Status of Artemisinin Resistance in Malaria Parasite Plasmodium falciparum from Molecular Analyses of the Kelch13 Gene in Southwestern Nigeria

Table 1

Genetic polymorphism and summary statistics of the Pfk13 gene in two population samples collected in two states of southwestern Nigeria.

StateNucleotide changeAmino acid changeNumberPopulation genetic parameters
SNPsHaplotypesHdTD

Edo (25)GGT-TGTG665330.1570.000960.00029-1.7333
GTA-GTCV666
CCG-CCAP553

Lagos (25)GTG-GTAV510120.0800.000320.00010-1.1575

Nonsynonymous mutation; synonymous mutation; SNPs, single nucleotide polymorphism; Hd, haplotype diversity; , number of segregating sites; , average number of pairwise nucleotide differences; TD, Tajima’s D.