Conscious Sedation versus General Anesthesia for Patients with Acute Ischemic Stroke Undergoing Endovascular Therapy: A Systematic Review and Meta-Analysis

Table 1

Characteristic and quality assessment of included studies in the meta-analysis.

Studies, year	Type of study	Type of stroke	Type of endovascular treatment	Number with CS versus GA	Selection	Comparability	Outcomes
Abou-Chebl et al. [8], 2010	Retrospective	AIS	Solitaire	85/196	++++		+
Davis et al. [12], 2012	Retrospective	AIS	IA rtPA and mechanical thrombectomy	48/48	++++	++	+
Hassan et al. [13], 2013	Retrospective	/	Endovascular procedure not specified	387/260	++++		+
John et al. [14], 2014	Retrospective	AIS	IA recanalization therapy	99/91	++++	++	+++
Jumaa et al. [15], 2010	Retrospective	Acute stroke	IA rtPA and mechanical thrombectomy	73/53	+++	+	+++
Just et al. [16], 2016	Retrospective cohort	AIS	IA rtPA, mechanical thrombectomy, thromboaspiration	67/42	++++	+	+++
Li et al. [17], 2014	Retrospective	AIS	IA rtPA, mechanical thrombectomy	74/35	++++	+	+++
Hendén et al. [18], 2017	RCT	AIS	IA rtPA	45/45	++++	++	+++
van den Berg et al. [9], 2015	Retrospective cohort	AIS	IA rtPA	278/70	++++		+++
Nichols et al. [19]; 2010	Pilot	AIS	IA rtPA	18/17	++++	++	+
Schönenberger et al. [10], 2016	RCT	AIS	Stent retriever or; thrombus aspiration	77/73	++++	++	+++
Slezak et al. [20], 2017	Prospective	AIS	Solitaire stent or IA rtPA	135/266	++++		+++
Sugg et al. [21], 2010	Retrospective	AIS	Mechanical thrombectomy	57/9	++++		+

Note. CS: conscious sedation; GA: general anesthesia; AIS: acute ischemic stroke; IA: intra-arterial; RCT: randomized controlled trials. , Irvine, California. plus indicates each quality item; 4 pluses are the maximum for the selection, 2 pluses are the maximum for the comparability, and 3 pluses are the maximum for completeness of the outcomes.