|
| Category | Group | Term | Count | | P-Value |
|
| GOTERM_MF_ALL | Upregulaged | sequence-specific double-stranded DNA binding (GO:1990837) | 14 | 14 | 3.40E-05 |
| transcription regulatory region sequence-specific DNA binding (GO:0000976) | 13 | 13 | 9.60E-05 |
| double-stranded DNA binding (GO:0003690) | 14 | 14 | 9.80E-05 |
| transcription factor activity, sequence-specific DNA binding (GO:0003700) | 16 | 16 | 5.90E-04 |
| nucleic acid binding transcription factor activity (GO:0001071) | 16 | 16 | 6.00E-04 |
| transcription regulatory region DNA binding (GO:0044212) | 13 | 13 | 6.50E-04 |
| regulatory region DNA binding (GO:0000975) | 13 | 13 | 6.70E-04 |
| regulatory region nucleic acid binding (GO:0001067) | 13 | 13 | 6.80E-04 |
| sulfur compound binding (GO:1901681) | 7 | 7 | 8.30E-04 |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding (GO:0000981) | 11 | 11 | 1.10E-03 |
| transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding (GO:0000982) | 8 | 8 | 1.20E-03 |
| receptor binding (GO:0005102) | 17 | 17 | 1.20E-03 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding (GO:0000978) | 8 | 8 | 1.50E-03 |
| transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding (GO:0001227) | 6 | 6 | 1.50E-03 |
| sequence-specific DNA binding (GO:0043565) | 14 | 14 | 1.60E-03 |
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding (GO:0001078) | 5 | 5 | 1.90E-03 |
| carbonate dehydratase activity (GO:0004089) | 3 | 3 | 1.90E-03 |
| core promoter proximal region sequence-specific DNA binding (GO:0000987) | 8 | 8 | 2.00E-03 |
| core promoter proximal region DNA binding (GO:0001159) | 8 | 8 | 2.10E-03 |
| RNA polymerase II regulatory region sequence-specific DNA binding (GO:0000977) | 10 | 10 | 2.10E-03 |
| RNA polymerase II regulatory region DNA binding (GO:0001012) | 10 | 10 | 2.20E-03 |
| activating transcription factor binding (GO:0033613) | 4 | 4 | 2.80E-03 |
| DNA binding (GO:0003677) | 23 | 23 | 3.20E-03 |
| metal ion binding (GO:0046872) | 32 | 32 | 3.70E-03 |
| ion binding (GO:0043167) | 33 | 33 | 4.20E-03 |
| cation binding (GO:0043169) | 32 | 32 | 4.40E-03 |
| RNA polymerase II activating transcription factor binding (GO:0001102) | 3 | 3 | 1.40E-02 |
| kinase binding (GO:0019900) | 8 | 8 | 2.30E-02 |
| hydro-lyase activity (GO:0016836) | 3 | 3 | 2.50E-02 |
| carboxyl-O-methyltransferase activity (GO:0010340) | 2 | 2 | 3.30E-02 |
| protein carboxyl O-methyltransferase activity (GO:0051998) | 2 | 2 | 3.30E-02 |
| binding (GO:0005488) | 75 | 75 | 3.80E-02 |
| protein kinase binding (GO:0019901) | 7 | 7 | 4.00E-02 |
| heparin binding (GO:0008201) | 4 | 4 | 4.00E-02 |
| enzyme binding (GO:0019899) | 15 | 15 | 4.10E-02 |
| modified amino acid binding (GO:0072341) | 3 | 3 | 4.40E-02 |
| carbon-oxygen lyase activity (GO:0016835) | 3 | 3 | 4.70E-02 |
| alcohol binding (GO:0043178) ) | 3 | 3 | 4.80E-02 |
| Downregulated | calcium ion binding (GO:0005509 | 32 | 10.8 | 8.80E-08 |
| growth factor binding (GO:0019838) | 11 | 3.7 | 2.10E-05 |
| laminin binding (GO:0043236) | 5 | 1.7 | 9.50E-04 |
| NADH pyrophosphatase activity (GO:0035529) | 3 | 1 | 2.10E-03 |
| phospholipid binding (GO:0005543) | 14 | 4.7 | 2.50E-03 |
| collagen binding (GO:0005518) | 6 | 2 | 2.60E-03 |
| cytokine activity (GO:0005125) | 10 | 3.4 | 6.00E-03 |
| fibronectin binding (GO:0001968) | 4 | 1.4 | 6.50E-03 |
| metal ion binding (GO:0046872) | 80 | 27 | 7.60E-03 |
| extracellular matrix binding (GO:0050840) | 5 | 1.7 | 7.80E-03 |
| sulfur compound binding (GO:1901681) | 10 | 3.4 | 8.10E-03 |
| lipid binding (GO:0008289) | 19 | 6.4 | 9.10E-03 |
| receptor antagonist activity (GO:0048019) | 3 | 1 | 9.10E-03 |
| receptor binding (GO:0005102) | 34 | 11.5 | 9.80E-03 |
| heparin binding (GO:0008201) | 8 | 2.7 | 9.90E-03 |
| cation binding (GO:0043169) | 80 | 27 | 1.00E-02 |
| calcium-dependent phospholipid binding (GO:0005544) | 5 | 1.7 | 1.10E-02 |
| glycosaminoglycan binding (GO:0005539) | 9 | 3 | 1.30E-02 |
| ion binding (GO:0043167) | 82 | 27.7 | 1.30E-02 |
| enzyme inhibitor activity (GO:0004857) | 13 | 4.4 | 1.40E-02 |
| receptor inhibitor activity (GO:0030547) | 3 | 1 | 1.80E-02 |
| nucleotide diphosphatase activity (GO:0004551) | 3 | 1 | 2.30E-02 |
| transforming growth factor beta binding (GO:0050431) | 3 | 1 | 2.30E-02 |
| metalloendopeptidase inhibitor activity (GO:0008191) | 3 | 1 | 2.30E-02 |
| protein homodimerization activity (GO:0042803) | 19 | 6.4 | 2.40E-02 |
| binding (GO:0005488) | 225 | 76 | 2.60E-02 |
| receptor regulator activity (GO:0030545) | 4 | 1.4 | 3.20E-02 |
| actin binding (GO:0003779) | 12 | 4.1 | 3.50E-02 |
| protein binding (GO:0005515) | 175 | 59.1 | 3.60E-02 |
| interleukin-1 receptor antagonist activity (GO:0005152) | 2 | 0.7 | 4.40E-02 |
| fibroblast growth factor binding (GO:0017134) | 3 | 1 | 4.50E-02 |
| cytoskeletal protein binding (GO:0008092) | 20 | 6.8 | 4.70E-02 |
|
