BioMed Research International / 2018 / Article / Fig 5

Research Article

Acetylation of HMGB1 by JNK1 Signaling Promotes LPS-Induced Peritoneal Mesothelial Cells Apoptosis

Figure 5

JNK1 knockout decreases peritoneal mesothelial cells apoptosis induced by LPS. (a) Representative images of TUNEL staining in parietal peritoneum of Wt and Jnk1-/- mice after LPS treatment. Scale bar: 20um. (b) Peritoneal mesothelial cells derived from Wt or Jnk1-/- mice and exposed to LPS, cell apoptosis was examined by flow cytometry. (c) Cell lysates were probed with antibodies against BAX and cleaved-caspase 3.

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