Review Article
The Dental Management of Patients at Risk of Medication-Related Osteonecrosis of the Jaw: New Paradigm of Primary Prevention
Table 4
Drug suspension for cancer patients; it must be agreed upon with the oncologist and performed according to the table.
| Drug holiday in cancer patients | Active pharmaceutical ingredient | Last administration | Resume treatment |
| Bisphosphonate (AR) | At least 1 week before | 4–6 weeks after | Denosumab (AR) | At least 1 week before | 4–6 weeks after | Bevacizumab (AA) | At least 6-7 weeks before | 4–6 weeks after | Sunitinib (AA) | At least 1 week before | 4–6 weeks after | Everolimus (AA) | At least 1 week before | 4–6 weeks after |
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