Short-Term Treatment with Esmolol Reverses Left Ventricular Hypertrophy in Adult Spontaneously Hypertensive Rats via Inhibition of Akt/NF-κB and NFATc4

Table 1

Systolic blood pressure and heart rate in WKY, SHR, and SHR-E.

Groups	Time treatment (hours)	SBP (mmHg)	HR (bpm)
WKY	0	126 ± 21	310 ± 20
	12	135 ± 18	317 ± 15
	24	119 ± 11	324 ± 21
	36	121 ± 22	319 ± 19
	48	127 ± 23	320 ± 12
SHR	0	190 ± 20	322 ± 15
	12	217 ± 25	311 ± 11
	24	198 ± 21	324 ± 18
	36	223 ± 12	312 ± 20
	48	205 ± 23	313 ± 16
SHR-E	0	199 ± 31	320 ± 13
	12	137 ± 15	229 ± 12
	24	139 ± 28	231 ± 10
	36	145 ± 11	219 ± 18
	48	143 ± 10	220 ± 13

WKY: Wistar-Kyoto rats; SHR: spontaneously hypertensive rats; SHR-E: esmolol-treated SHR rats; SBP: systolic blood pressure; HR: heart rate. Values are shown as mean ± SEM. versus WKY and versus WKY; versus untreated SHR and versus untreated SHR.