Unsupervised versus Supervised Identification of Prognostic Factors in Patients with Localized Retroperitoneal Sarcoma: A Data Clustering and Mahalanobis Distance Approach

Table 2

Clinical descriptors and prognostic reclassification. Each variable was reclassified according to the prognostic information deriving from literature data and clinical expertise. Each reclassification group could range from 0 (better prognosis) to 3 (worst prognosis). For more details on the recoding, see the Appendix.

Clinical characteristics	Values	Reclassification
Age (years)	<50	1
	51–60	1.5
	61–65	2
	66–70	2.5
	70–75	3
Histology	WDLPS, SFT	1
	Myxoid LPS	1.5
	Pleomorphic LPS, fibrosarcoma	2
	LMS, DDLPS	2.5
	MPNST, NOS sarcoma	3
FNCLLC grading	G1	1
	G2	2
	G3	3
Size (cm)	<10	1
	11–15	1.5
	16–20	2
	20–30	2.5
	30–45	3
Response after chemo- and radiotherapy	PR	1
	SD	2
	PD	3
Type of resection	No resection	1
	R0/R1	2
	R2	3
DFI (months)	Never relapsed	0
	>36	0.5
	24–36	1
	12–24	1.5
	6–12	2
	0–6	2.5
	Never NED	3
Relapse pattern	No relapse	0
	Local	1
	Distant	2
	Local + distant	3
First type of retreatment at recurrence	Surgery, surgery + RT	1
	CT followed by surgery	1.5
	CT or RT	2
	Debulking surgery, no surgery	3