Early Enhanced Leucine-Rich α-2-Glycoprotein-1 Expression in Glomerular Endothelial Cells of Type 2 Diabetic Nephropathy Model Mice

Figure 3

Enhanced glomerular LRG1 mRNA expression in db/db mice at 16 weeks of age. Quantitative analysis of angiogenesis- and fibrosis-related gene expression in glomeruli identified by the LMD method in db/m and db/db mice at 16 weeks of age. (a) LRG1, (b) VEGF, (c) VEGFR-2, (d) TFG-β, (e) Collagen IV, (f) PAI-1, (g) ENG, and (h) TβRII. Values are expressed as the mean ± SEM (n = 4–6 in each group). P < 0.05, versus db/m mice, unpaired t-test.

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