Research Article

Early Enhanced Leucine-Rich α-2-Glycoprotein-1 Expression in Glomerular Endothelial Cells of Type 2 Diabetic Nephropathy Model Mice

Table 1

Body weight, blood glucose, kidney weight, plasma creatinine, and albuminuria of db/db and db/m mice.

Variable16W24W
db/mdb/dbdb/mdb/db
(n=6)(n=6)(n=4)(n=4)

Body weight (g)29.2 ± 1.348.2 ± 0.737.0 ± 0.552.2 ± 4.8
Blood glucose (mg/dl)134.8 ± 5.8>600130 ± 6.7574 ± 26
Kidney weight (mg)182.3 ± 6.7217.3 ± 8.5225.0 ± 6.7263.3 ± 5.8
Plasma creatinine (mg/dl)0.12 ± 0.220.11 ± 0.10.08 ± 0.010.09 ± 0.02
Albuminuria (mg/mg⋅Cr)0.25 ± 0.020.67 ± 0.160.04 ± 0.011.05 ± 0.53

All values are means ± SEM.
P < 0.05, P <0.01, vs db/m mice at the same age, unpaired t-test.