Optimization of the Cytotoxic Activity of Three Streptomyces Strains Isolated from Guaviare River Sediments (Colombia, South America)

Table 2

Determination of IC₅₀ values for the extracts of strains 73, 386, and 519 cultivated in ISP 2; against prostate (PC3), lung (A549), and breast (MDA-MB-231) tumour lines. The results are expressed as an average ± standard deviation (n=3).

IC50(ppm)
Isolate	PC3	A549	MDA-MB-231
73	64.84±3.85	67.69±2.42	43.24±1.96
386	6.14±2.07	33.17±2.67	70.72±4.87
519	64.58±4.76	60.54±2.86	45.89±2.36