Optimization of the Cytotoxic Activity of Three Streptomyces Strains Isolated from Guaviare River Sediments (Colombia, South America)

Table 7

Analysis of variance for the fit second order polynomial model and lack of fit for the cytotoxic percent by composite central design for the strain Streptomyces gramineus (386). SS: sum of squares, DF: degrees of freedom, MSS: mean sum of squares.

Source	Sum of squares	DF	Mean square	F value	p-value
Model	101.406	6	16.901	8.746	0.0037
A	0.162	1	0.162	0.084	0.7790
B	18.572	1	18.572	9.611	0.0147
C	32.920	1	32.920	17.037	0.0033
AC	90.358	1	90.358	46.762	0.0001
BC	0.644	1	0.644	0.333	0.5795
C2	1.987	1	1.987	1.028	0.3402
Residual	15.458	8	1.932
Lack of Fit	12.147	4	3.037	3.669	0.1180
Pure Error	3.310	4	0.827
Cor Total	116.865	14