Russell Bodies and Russell Body Inflammatory Polyp in the Colorectum: A Review of Clinicopathologic Features

Table 1

Case reports of Russell body containing Mott cells in the colorectum.

Case no. (Source)	Age, year/ Sex	Location	Clinical Presentation	Endoscopic; findings	Histopathologic; findings	Ancillary Studies
1 (Coates et al., 2017 [4])	62/Male	Sigmoid Colon	Average risk screening colonoscopy, no GI complaints	<5 mm Erythematous polyp; severe diverticulosis	Inflammatory polyp with Russell bodies in the lamina propria.	CD138 and CD79a positive; polyclonal
2. (Muthukumarana et al., 2015 [5])	44/Female	Colon	Diarrhea, abdominal pain, nausea and vomiting. Status post kidney and pancreas transplant with immunosuppression.	Normal colonic endoscopy; no colonic polyp	Chronic lymphoplasmacytic infiltrate with Mott cells within the lamina propria in colon, terminal ileum, duodenum and stomach	PAS positive; CD138 positive; polyclonal
3 (Brink et al., 1999 [6])	53/Female	Rectum	Indication not provided. No evidence for malignant myeloma or a gammopathy.	Rectal polyp, not further specified	Tubulovillous adenoma with high-grade epithelial dysplasia and dense plasma cell infiltrates containing Russell bodies and Mott cells	IgG monoclonal for kappa light chain

polyclonal nature confirmed by concomitant expression of kappa and lambda light chain.