Outcome of Irrigation and Debridement after Failed Two-Stage Reimplantation for Periprosthetic Joint Infection

Table 2

Successful cases with organism type, resistogram, and antibiotics; failed two-stage revision was done at a tertiary referral center; prior surgeries (column 2) were done in external clinics.

Patient	Revision surgeries prior to failed two-stage revision	Organism type: failed two-stage revision	Antibiotics preoperative	Number of surgeries (I&D)	Organism type: I&D	Antibiotics postoperativ	Resistant; against
1	Two-stage revision	MRSE	Va, Ti, Ri	1	MRSE	Va, Ti, Ri	Ox, Ri, Ci, Ge, Cl, Im
2	-	MRSE	Le, Ri	7	MRSE	Le, Va, Ri	Ox, Ci, Ge, Cl
3	Revision due to bursitis intertrochanterica	Staph. capitis	Le, Ri	1	Strepto. intermedius	Le, Ri	Cl
7	-	Staph. aureus	-	8	Staph. aureus	Le, Fl, Ri	-
8	Bursectomy, Exchange of cup		Le, Ri	7	MRSE	Va, Cl, Ri	Ox, Ce, Im
9	Soft tissue revision	Strepto. agalactiae	Fl, Ri	1	Enterococcus faecalis	Fl, Am, Ri	Ge, Cl, Ce
11	-		Le, Ri	2	Staph. aureus	Le, Ri	-
12	Two-stage revision		Le, Ri	5	(1) Enterococcus faecalis; (2) Peptostrepto. magnus	Le, Amp, Ri	(1) Ge, Cl; (2) -
13	ORIF (tibiaplateau fracture)	MRSE	-	6	Escherichia coli	Le, Ce, Ri	-
14	-	Staph. epi	Le, Ri	11	MRSE	Va, Ri	Ox, Ge, Cl, Ce, Va, Im
18	Two-stage revision	Staph. aureus	-	7	Escherichia coli	Me, Ri	Le, Ci,
19	3x two-stage revision	Strept. simulans	Le, Ri	5	Escherichia coli	Le, Ri	-

MRSE = methicillin-resistant staphylococcus epidermidis, Ox = oxacillin, Ri = rifampicin, Le = levofloxacin, Ci = ciprofloxacin, To = tobramycin, Fl = flucloxacillin, Ge = gentamicin, Cl = clindamycin, Ce = cefuroxime, Va, = vancomycin, Li = linezolid, Im = imipenem, Ti = tigecycline, Am = amoxicillin, Amp = ampicillin, Mo = moxifloxacin, Me = meropenem